How to start a daycare in Missouri.

Missouri Department of Elementary and Secondary Education (DESE) licenses child care centers in Missouri. These are the steps, each with the state's own page.

Steps checked on the state's own pages, November 4, 2026.

Opening a child care center in Missouri, step by step

  1. Take the licensing orientation

    Your first step is the free Child Care Licensing Orientation.

    Source: Start a Group Child Care Home or Child Care Center
  2. Check local rules

    Ask your city or local government about zoning, building and other local rules for child care.

    Source: Steps to Becoming Licensed: Group Child Care Homes & Centers
  3. Send your application

    Send the Application for License to Operate a Child Care Facility to your regional office.

    Source: Steps to Becoming Licensed: Group Child Care Homes & Centers
  4. Meet your Compliance Inspector

    You get a Departmental Vendor Number. A Compliance Inspector then works with you on licensing.

    Source: Steps to Becoming Licensed: Group Child Care Homes & Centers
  5. Complete a site review

    Your Compliance Inspector looks over your planned space and notes any changes it needs.

    Source: Steps to Becoming Licensed: Group Child Care Homes & Centers
  6. Write policies and gather documents

    Write your program policies and gather the documents the rules require. Send them to your Compliance Inspector.

    Source: Steps to Becoming Licensed: Group Child Care Homes & Centers
  7. Get background screening

    Staff, caregivers and volunteers need fingerprints and a Family Care Safety Registry screening.

    Source: Steps to Becoming Licensed: Group Child Care Homes & Centers
  8. Pass your inspections

    Pass your fire, sanitation and licensing inspections. Then the Office of Childhood can issue your license.

    Source: Steps to Becoming Licensed: Group Child Care Homes & Centers

At a glance

Who licenses centers
Missouri Department of Elementary and Secondary Education (DESE), Office of Childhood. Issues the child care license a facility needs to operate in Missouri.Source: Start a Child Care Program
License needed for
More than 6 children, or more than 3 under age 2Source: Child Care Licensing
Center size
Any number of children, away from the provider's living quartersSource: Start a Group Child Care Home or Child Care Center
Inspections
Fire and sanitation once a year, licensing rules twice a yearSource: Start a Child Care Program
Application deadline
Void if the rules are not met within 6 monthsSource: Steps to Becoming Licensed: Group Child Care Homes & Centers

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Questions, answered

How do I start a daycare in Missouri?

The first step: Take the licensing orientation. All 8 steps are on this page, each with the state's own link.

Who licenses child care centers in Missouri?

Missouri Department of Elementary and Secondary Education (DESE), Office of Childhood. Issues the child care license a facility needs to operate in Missouri.

About this page

Steps checked on the state's own pages, November 4, 2026.

This page is a summary of the state's own pages. It is not legal advice, and rules change.

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